Expression of parvin-β is a prognostic factor for patients with urothelial cell carcinoma of the upper urinary tract

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The prognostic significance of vasohibin-1 expression in patients with upper urinary tract urothelial carcinoma.

PURPOSE Vasohibin-1 (VASH1) is a novel angiogenic molecule that is specifically expressed in activated vascular endothelial cells, and the status of VASH1 expression has been documented in cancer angiogenesis. The aim of this study was to address the prognostic value of VASH1 expression in upper urinary tract urothelial carcinomas (UTUC). EXPERIMENTAL DESIGN We retrospectively analyzed the cl...

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Preoperative serum albumin as a prognostic factor in patients with upper urinary tract urothelial carcinoma.

PURPOSE The study evaluated whether preoperative measures of the C-reactive protein-systemic inflammatory response may predict cancer survival independent of tumor stage in patients with upper urinary tract urothelial carcinoma (UTUC). MATERIALS AND METHODS Between September 1999 and October 2010, 181 patients submitted to radical nephroureterectomy were available for evaluation. Multivariate...

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Re: Preoperative serum albumin as a prognostic factor in patients with upper urinary tract urothelial carcinoma.

The publication on “Preoperative serum albumin and upper urinary tract urothelial carcinoma” is very interesting (1). Ku et al. reported that “hypoalbuminemia is an independent marker of poor prognosis in patients with upper urinary tract urothelial carcinoma (1).” Indeed, there are many recent reports confirming the importance of pretherapeutic serum albumin level (1, 2). This parameter can re...

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Urothelial Cell Carcinoma of the Upper Urinary Tract: Introduction

Urothelium is the specialized epithelium that covers the urinary collecting system from the tips of the renal papillae to the prostatic urethra. Tumors of the urothelium can be benign but the vast majority are malignant carcinomas. Carcinomas of the urothelium are common and the upper urinary tract is the affected site in roughly 5% of cases. Similarly, 5–10% of tumors that involve the kidney a...

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Expression of Phospho-ELK1 and Its Prognostic Significance in Urothelial Carcinoma of the Upper Urinary Tract

Using preclinical models, we have recently found that ELK1, a transcriptional factor that activates downstream targets, including c-fos proto-oncogene, induces bladder cancer outgrowth. Here, we immunohistochemically determined the expression status of phospho-ELK1, an activated form of ELK1, in upper urinary tract urothelial carcinoma (UUTUC). Overall, phospho-ELK1 was positive in 47 (47.5%; 3...

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ژورنال

عنوان ژورنال: British Journal of Cancer

سال: 2010

ISSN: 0007-0920,1532-1827

DOI: 10.1038/sj.bjc.6605835